Open AccessGenetics of susceptibility to human helminthiasis
Author(s) -
Начева,
Л В Начева,
Кутихин,
Anton G. Kutikhin
Publication year - 2016
Publication title -
rossijskij parazitologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2541-7843
pISSN - 1998-8435
DOI - 10.12737/21667
Subject(s) - helminthiasis , biology , gene , schistosomiasis , host (biology) , genetics , immunology , helminths
Objective of research: to provide the analysis of literature sources describing the influence of host genes on genetic susceptibility to helminthiasis and the features of its pathogenesis. Results and discussion: all recent scientific works dedicated to the influence of host genes on genetic susceptibility to helminthiasis and the features of its pathogenesis were considered. The most important determinants of impact of host genes on genetic susceptibility to helminthiasis are gene polymorphisms TAP for echinococcosis, variants of genetic loci SM1 and SM2 for bilharziasis (schistosomiasis), and gene polymorphisms HLA for all three parasitic diseases described in this article.