Genetics of susceptibility to human helminthiasis | Zendy

Начева | Zendy; Л В Начева | Zendy; Кутихин | Zendy; Anton G. Kutikhin | Zendy

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Genetics of susceptibility to human helminthiasis

Author(s) -

Начева,

Л В Начева,

Кутихин,

Anton G. Kutikhin

Publication year - 2016

Publication title -

russian journal of parasitology

Language(s) - English

Resource type - Journals

eISSN - 2541-7843

pISSN - 1998-8435

DOI - 10.12737/21667

Subject(s) - helminthiasis , biology , gene , schistosomiasis , host (biology) , genetics , immunology , helminths

Objective of research: to provide the analysis of literature sources describing the influence of host genes on genetic susceptibility to helminthiasis and the features of its pathogenesis. Results and discussion: all recent scientific works dedicated to the influence of host genes on genetic susceptibility to helminthiasis and the features of its pathogenesis were considered. The most important determinants of impact of host genes on genetic susceptibility to helminthiasis are gene polymorphisms TAP for echinococcosis, variants of genetic loci SM1 and SM2 for bilharziasis (schistosomiasis), and gene polymorphisms HLA for all three parasitic diseases described in this article.

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