ESTIMATION OF REPRODUCTIVE TOXICITY OF THE COMPLEX PLANT REMEDY �TIREOTON� | Zendy

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ESTIMATION OF REPRODUCTIVE TOXICITY OF THE COMPLEX PLANT REMEDY �TIREOTON�

Author(s) -

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И.П. Убеева,

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С. М. Николаев,

Я. Г. Разуваева,

Н. В. Верлан,

Viktoriya Ayusheeva

Publication year - 2016

Publication title -

бюллетень восточно-сибирского научного центра сибирского отделения российской академии медицинских наук

Language(s) - English

Resource type - Journals

ISSN - 1811-0649

DOI - 10.12737/20618

Subject(s) - reproductive toxicity , toxicity , embryo , teratology , pregnancy , biology , physiology , toxicology , reproductive system , andrology , fetus , medicine , endocrinology , genetics

To study the probable negative influence of the complex remedy Tireoton on the reproductive function of the laboratory animals the following tests have been carried out, namely the probable occurrence of embryo-toxicity, teratogenicity, foetotoxicity and its influence on the postnatal development of the laboratory animals progeny. The experiments have been carried out of the white Wistar rats. It has been established that the Tireoton at the doses of 75 and 750 mg/ kg has no embryotoxic, teratogenic and fetotoxical effect. The introduction of the Tireoton at the dose of 750 mg/kg since 6th to 19th day of pregnancy does not influence on the postnatal development of white rats progeny.

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