Open AccessNano ZnO and its Perspective in Anti-Cancer Activities
Author(s) -
N Shobhaa,
N Nandab,
B.M. Nagabhushana
Publication year - 2017
Publication title -
mapana journal of sciences
Language(s) - English
Resource type - Journals
ISSN - 0975-3303
DOI - 10.12723/mjs.41.5
Subject(s) - cytotoxicity , zinc , nanoparticle , cancer , nanotechnology , reactive oxygen species , cancer cell , materials science , apoptosis , chemistry , medicine , biochemistry , metallurgy , in vitro
Several methods are used to counter the deadly disease cancer. Zinc oxide nanoparticles (ZnO NPs) is one of the metal oxide nanoparticles which had been used in anti-cancer activities due to its large bandwidth and high exciting binding energy and it has potential applications like antibacterial, antifungal, anti-diabetic, anti-inflammatory, wound healing, antioxidant, optic properties and also which holds promise to treat cancer effectively. Studies have shown that Zinc metal oxide nano particles induce cytotoxicity in cancer cells. The mechanism for antitumor could work through apoptosis or the generation of reactive oxygen species or and necrosis, among other possibilities. This review is on some of the most significant antitumor results obtained with zinc oxide nanoparticles depending on their size, surface morphology, methods of preparation and also cytotoxicity result.