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Central sensitization and pain hypersensitivity: Some critical considerations.
Author(s) -
Emanuel N. van den Broeke
Publication year - 2018
Publication title -
f1000research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.099
H-Index - 60
ISSN - 2046-1402
DOI - 10.12688/f1000research.15956.2
Subject(s) - central sensitization , sensitization , medicine , central pain , neuroscience , immunology , psychology , anesthesia , nociception , receptor
Since its discovery, central sensitization has gained enormous popularity. It is widely used to explain pain hypersensitivity in a wide range of clinical pain conditions. However, at present there is no general consensus on the definition of central sensitization. Moreover, the use of the term central sensitization in the clinical domain has been criticized. The aim of this paper is to foster the discussion on the definition of central sensitization and its use.

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