Open AccessADAM10 expression in gastric adenocarcinoma: Results of a curative gastrectomy cohort
Author(s) -
Hüseyin Alakuş,
Mustafa Kaya,
Hatice Özer,
Hulusi Eğilmez,
Kürşat Karadayı
Publication year - 2021
Publication title -
pakistan journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.316
H-Index - 30
eISSN - 1682-024X
pISSN - 1681-715X
DOI - 10.12669/pjms.37.2.3613
Subject(s) - medicine , immunohistochemistry , adam10 , adenocarcinoma , univariate analysis , gastrectomy , cancer , lymph node , gastric adenocarcinoma , multivariate analysis , gastroenterology , stage (stratigraphy) , pathology , oncology , metalloproteinase , disintegrin , matrix metalloproteinase , paleontology , biology
Gastric cancer is among the most common human cancers with high mortality rates. ADAM10, a member of the ADAM (a disintegrin and metalloproteinase) family has also been found to be associated with gastric carcinoma and has been suggested as a potential therapeutic target. Here, we investigated the association of ADAM10 expression with prognosis in gastric adenocarcinoma patients that underwent gastric resection with D2 lymph node dissection.