Open AccessAssessment of cell free mitochondrial DNA as a biomarker of disease severity in different viral infections
Author(s) -
Zain Ali,
Shahid Waseem,
Riffat Aysha Anis,
Mariam Anees
Publication year - 2020
Publication title -
pakistan journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.316
H-Index - 30
eISSN - 1682-024X
pISSN - 1681-715X
DOI - 10.12669/pjms.36.5.2476
Subject(s) - viral load , medicine , biomarker , mitochondrial dna , virology , immunology , dna , real time polymerase chain reaction , virus , biology , gene , genetics
Cell Free mitochondrial DNA (CF mt-DNA) has emerged as a novel biomarker to investigate disease pathophysiology of different infections. The present study was designed to elucidate the association between CF mt-DNA, IL-6 and viral load in HIV, HBV and HCV infections and predict its role as a potential biomarker to assess the disease severity in viral infections.