Open AccessDetection and Genotyping of Helicobacter pylori among Gastric ulcer and Cancer Patients from Saudi Arabia
Author(s) -
Fehmida Bibi,
Sana Alvi,
Sara Ali Sawan,
Muhammad Yasir,
Ali Sawan,
Asif A. Jiman-Fatani,
Esam I. Azhar
Publication year - 2017
Publication title -
pakistan journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.316
H-Index - 30
eISSN - 1682-024X
pISSN - 1681-715X
DOI - 10.12669/pjms.332.12024
Subject(s) - medicine , helicobacter pylori , genotyping , gastroenterology , cancer , genotype , gene , genetics , biology
Helicobacter pylori ( H. pylori ) infection is cause of several gastrointestinal diseases in humans. Virulence genes of H. pylori are associated with severity of disease and vary geographically. The aim of present study was to detect H. pylori in formalin-fixed paraffin-embedded (FFPE) tissues and further investigate prevalence of babA 2, cag A, iceA1 , iceA2, vacA s1/s2 and vacA m1/m2 genotypes in H. pylori from gastric cancer (GC) and gastric ulcer (GU) patients' biopsy samples.