A case of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) presenting as post-infectious manifestation of SARS-CoV-2 infection | Zendy

Ishwariya Rajendran | Zendy; Madhu Dutta Natarajan | Zendy; Pooja Narwani | Zendy; Omran Alzouabi | Zendy; Khalil Kawafi | Zendy; Navin Khanna | Zendy

Open Access

A case of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) presenting as post-infectious manifestation of SARS-CoV-2 infection

Author(s) -

Ishwariya Rajendran,

Madhu Dutta Natarajan,

Pooja Narwani,

Omran Alzouabi,

Khalil Kawafi,

Navin Khanna

Publication year - 2021

Publication title -

bjr|case reports

Language(s) - English

Resource type - Journals

ISSN - 2055-7159

DOI - 10.1259/bjrcr.20210020

Subject(s) - cadasil , leukoencephalopathy , hyperintensity , medicine , encephalopathy , pathology , acute disseminated encephalomyelitis , progressive multifocal leukoencephalopathy , leukoaraiosis , white matter , encephalitis , dementia , magnetic resonance imaging , disease , multiple sclerosis , virology , radiology , immunology , virus

White matter hyperintensities (WMHs) lacunar infarcts and cerebral microbleeds are well-established features associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Increasing case reports and series recounts a wide array of neurological manifestations of COVID-19 including acute cerebrovascular disease, encephalopathy, encephalitis and demyelination. Recently association between COVID-19 and CADASIL has been identified. We describe an unusual case of CADASIL diagnosed as a possible post-infectious manifestation of COVID-19 patient with imaging features closely resembling post-infectious encephalomyelitis.

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