Open AccessIncidental cardiac uptake in bone scintigraphy: increased importance and association with cardiac amyloidosis
Author(s) -
Francis T. Delaney,
P. Dempsey,
Ivan Welaratne,
Bryan Buckley,
D O’Sullivan,
Martin O’Connell
Publication year - 2021
Publication title -
bjr case reports
Language(s) - English
Resource type - Journals
ISSN - 2055-7159
DOI - 10.1259/bjrcr.20200161
Subject(s) - medicine , bone scintigraphy , cardiac amyloidosis , scintigraphy , radiology , coronary artery disease , amyloidosis , differential diagnosis , cardiology , pathology
Extraosseous radiotracer uptake during bone scintigraphy must be carefully assessed and it offers the potential to detect previously undiagnosed disease processes. A range of neoplastic, metabolic, traumatic, ischaemic and inflammatory disorders can cause soft tissue accumulation of bone avid radiopharmaceuticals. Accordingly, cardiac uptake in bone scintigraphy has a broad differential diagnosis and is commonly attributed to ischaemia/infarction related to coronary artery disease. However, there has been renewed focus on incidental cardiac uptake in recent years in light of significant developments in the diagnosis and management of cardiac amyloidosis.