Open AccessEstablishment of a colony of mice free from lymphocytic choriomeningitis in kenya
Author(s) -
John E. Cooper
Publication year - 1973
Publication title -
laboratory animals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.62
H-Index - 63
eISSN - 1758-1117
pISSN - 0023-6772
DOI - 10.1258/002367773781008713
Subject(s) - lymphocytic choriomeningitis , animals laboratory , medicine , biology , veterinary medicine , toxicology , immunology , environmental health , immune system , population , cd8 , research methodology
The introduction of mice free from lymphocytic choriomeningitis (LCM) necessitated a rigorous program of elimination of LCM-infected mice, followed by disinfection and rodent-proofing of buildings. The program was phased to ensure a continuing supply of experimental mice to the laboratory. The maintenance of the LCM-free colony, including strict hygienic precautions such as the wearing of protective clothing and the disinfection of food, bedding and equipment, is described. The value of LCM-free mice in laboratory work and the use of the colony in testing other laboratory and wild rodents for LCM are briefly discussed.