Exercise-Induced Oxidative DNA Damage and Lymphocytopenia in Sedentary Young Males | Zendy

Yuko Tanimura | Zendy; Kazuhiro Shimizu | Zendy; Kai Tanabe | Zendy; Takeshi Otsuki | Zendy; Ryohei Yamauchi | Zendy; Yuichi Matsubara | Zendy; Motoyuki Iemitsu | Zendy; Seiji Maeda | Zendy; Ryuichi Ajisaka | Zendy

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Exercise-Induced Oxidative DNA Damage and Lymphocytopenia in Sedentary Young Males

Author(s) -

Yuko Tanimura,

Kazuhiro Shimizu,

Kai Tanabe,

Takeshi Otsuki,

Ryohei Yamauchi,

Yuichi Matsubara,

Motoyuki Iemitsu,

Seiji Maeda,

Ryuichi Ajisaka

Publication year - 2008

Publication title -

medicine and science in sports and exercise

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.703

H-Index - 224

eISSN - 1530-0315

pISSN - 0195-9131

DOI - 10.1249/mss.0b013e31817242cf

Subject(s) - lymphocytopenia , dna damage , lymphocyte , oxidative stress , medicine , endocrinology , reactive oxygen species , immunology , chemistry , biology , dna , biochemistry

Post high-intensity exercise lymphocytopenia is well documented, but its underlying mechanisms have not been fully elucidated. A possible mechanism is a reactive oxygen species-induced DNA damage after high-intensity exercise. Furthermore, lymphocyte apoptosis related to DNA damage might contribute to exercise-induced lymphocytopenia.

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