Open AccessExercise Training-Induced Changes in Coagulation Factors in Older Adults
Author(s) -
Michael M. Lockard,
Rakesh Gopinathannair,
Chad M. Paton,
Dana A. Phares,
James M. Hagbèrg
Publication year - 2007
Publication title -
medicine and science in sports and exercise
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/mss.0b013e31802eff4b
Subject(s) - medicine , aerobic exercise , confounding , coagulation , aerobic capacity , lipid profile , lipoprotein , cardiology , cholesterol , endocrinology
The coagulation cascade plays a critical role in the development of cardiovascular disease (CVD). Elevated plasma prothrombin fragment 1 + 2 (F1 + 2) and factor VIII antigen (FVIII:Ag) levels have been associated with a hypercoagulable state, enhancing the risk for vascular thrombotic events. Aerobic training is known to reduce CVD risk, and an improved coagulation profile may contribute to this reduction.