
Myokine Expression and Tumor-Suppressive Effect of Serum after 12 wk of Exercise in Prostate Cancer Patients on ADT
Author(s) -
Jin-Soo Kim,
Rebekah L. Wilson,
Dennis R. Taaffe,
Daniel A. Galvão,
Elin S. Gray,
Robert U. Newton
Publication year - 2021
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/mss.0000000000002783
Subject(s) - myokine , du145 , medicine , endocrinology , prostate cancer , cancer , skeletal muscle , lncap
Although several mechanisms have been proposed for the tumor-suppressive effect of exercise, little attention has been given to myokines, even though skeletal muscle is heavily recruited during exercise resulting in myokine surges. We measured resting serum myokine levels before and after an exercise-based intervention and the effect of this serum on prostate cancer cell growth.