Open AccessChronic Exercise Protects against the Progression of Renal Cyst Growth and Dysfunction in Rats with Polycystic Kidney Disease
Author(s) -
Jiahe Qiu,
Yoichi Sato,
Li Xu,
Tetsuji Miura,
Masahiro Kohzuki,
Osamu Ito
Publication year - 2021
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/mss.0000000000002737
Subject(s) - endocrinology , medicine , polycystic kidney disease , kidney disease , kidney , renal function , creatinine
Polycystic kidney disease (PKD) is a genetic disorder characterized by the progressive enlargement of renal epithelial cysts and renal dysfunction. Previous studies have reported the beneficial effects of chronic exercise on chronic kidney disease. However, the effects of chronic exercise have not been fully examined in PKD patients or models. The effects of chronic exercise on the progression of PKD were investigated in a polycystic kidney (PCK) rat model.