Open AccessInflammation Mediates Exercise Effects on Fatigue in Patients with Breast Cancer
Author(s) -
Anouk E. Hiensch,
Sara Mijwel,
David Bargiela,
Yvonne Wengström,
Anne M. May,
Helene Rundqvist
Publication year - 2020
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/mss.0000000000002490
Subject(s) - medicine , high intensity interval training , interval training , aerobic exercise , inflammation , randomized controlled trial , confidence interval , breast cancer , oncology , physical therapy , cancer
The randomized controlled OptiTrain trial showed beneficial effects on fatigue after a 16-wk exercise intervention in patients with breast cancer undergoing adjuvant chemotherapy. We hypothesize that exercise alters systemic inflammation and that this partially mediates the beneficial effects of exercise on fatigue.