Open AccessVentilatory Responsiveness during Exercise and Performance Impairment in Acute Hypoxia
Author(s) -
Keren Constantini,
Anna C. Bouillet,
Chad C. Wiggins,
Bruce Martin,
Robert F. Chapman
Publication year - 2020
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/mss.0000000000002466
Subject(s) - hypoxia (environmental) , hypoxic ventilatory response , medicine , ventilation (architecture) , cycling , cardiology , respiratory minute volume , anesthesia , respiratory system , oxygen , chemistry , mechanical engineering , organic chemistry , archaeology , engineering , history
An adequate increase in minute ventilation to defend arterial oxyhemoglobin saturation (SpO2) during hypoxic exercise is commonly viewed as an important factor contributing to large inter-individual variations in the degree of exercise performance impairment in hypoxia. Although the hypoxic ventilatory response (HVR) could provide insight into the underpinnings of such impairments, it is typically measured at rest under isocapnic conditions. Thus, we aimed to determine whether 1) HVR at rest and during exercise are similar and 2) exercise HVR is related to the degree of impairment in cycling time trial (TT) performance from normoxia to acute hypoxia (∆TT).