Open AccessAssociation between Mitochondrial DNA Sequence Variants and V˙O2 max Trainability
Author(s) -
Heather L. Vellers,
Kirsten C. Verhein,
Adam Burkholder,
JaeHoon Lee,
YoungMin Kim,
J. Timothy Lightfoot,
Min Shi,
Clarice R. Weinberg,
Mark A. Sarzynski,
Claude Bouchard,
Steven R. Kleeberger
Publication year - 2020
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/mss.0000000000002390
Subject(s) - haplogroup , mitochondrial dna , heteroplasmy , hypervariable region , human mitochondrial dna haplogroup , genetics , biology , microbiology and biotechnology , polymerase chain reaction , gene , haplotype , allele
We designed the study to determine whether mitochondrial DNA (mtDNA) haplogroup, sequence, and heteroplasmy differed between individuals previously characterized as low (LR) or high responders (HR) as defined by their maximal oxygen uptake response to a standardized aerobic exercise training program.