Open AccessCardiorespiratory Fitness Normalized to Fat-Free Mass and Mortality Risk
Author(s) -
Mary T. Imboden,
Leonard A. Kaminsky,
James E. Peterman,
Haylee L. Hutzler,
M. H. Whaley,
Bradley S. Fleenor,
Matthew P. Harber
Publication year - 2020
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/mss.0000000000002289
Subject(s) - cardiorespiratory fitness , medicine , fat free mass , proportional hazards model , hazard ratio , lean body mass , demography , cardiology , physical therapy , fat mass , body mass index , body weight , confidence interval , sociology
Cardiorespiratory fitness (CRF) is known to be directly related to fat-free mass (FFM), therefore, it has been suggested that normalizing CRF to FFM (V˙O2peakFFM) may be the most accurate expression of CRF as related to exercise performance and cardiorespiratory function. However, the influence of V˙O2peakFFM (mL·kg FFM·min) on predicting mortality has been largely unexplored. This study aimed to primarily assess the relationship between V˙O2peakFFM and all-cause and disease-specific mortality risk in apparently healthy adults. Further, this study sought to compare the predictive ability of V˙O2peakFFM to V˙O2peak normalized to total body weight (V˙O2peakTBW) for mortality outcomes.