Open AccessDermal Calcium Loss Is Not the Primary Determinant of Parathyroid Hormone Secretion during Exercise
Author(s) -
Wendy M. Kohrt,
Pamela Wolfe,
Vanessa D. Sherk,
Sarah J. Wherry,
Toby Wellington,
Edward L. Melanson,
Christine M. Swanson,
Connie M. Weaver,
Rebecca S. Boxer
Publication year - 2019
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/mss.0000000000002017
Subject(s) - endocrinology , medicine , parathyroid hormone , bone resorption , chemistry , calcium , n terminal telopeptide , aerobic exercise , calcium metabolism , osteocalcin , biochemistry , alkaline phosphatase , enzyme
Exercise can cause a decrease in serum ionized calcium (iCa) concentration, which stimulates parathyroid hormone (PTH) secretion and activates bone resorption. We postulated that dermal Ca loss during cycling exercise is the major determinant of the serum iCa, PTH, and bone resorption (C-terminal telopeptide of type 1 collagen [CTX]) responses.