Open AccessExercise-induced Changes in Soluble ST2 Concentrations in Marathon Runners
Author(s) -
Vincent L. Aengevaeren,
Roland R.J. van Kimmenade,
Maria T. E. Hopman,
Niels van Royen,
James V. Snider,
James L. Januzzi,
Keith George,
Thijs M. H. Eijsvogels
Publication year - 2019
Publication title -
medicine and science in sports and exercise
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/mss.0000000000001806
Subject(s) - medicine , cardiology , troponin i , troponin , cohort , biomarker , troponin t , heart rate , physical therapy , blood pressure , myocardial infarction , biochemistry , chemistry
Previous studies have suggested that extreme endurance exercise may induce cardiac microdamage that could lead to subsequent myocardial fibrosis. Soluble suppression of tumorigenicity 2 (sST2) is a cardiac biomarker for assessment of myocardial fibrosis, inflammation, and strain. We evaluated baseline and exercise-induced sST2 concentrations in a heterogeneous cohort of marathon runners to identify predictors for sST2 concentrations.