Open AccessVascular Nitric Oxide–Superoxide Balance and Thrombus Formation after Acute Exercise
Author(s) -
Kamil Przyborowski,
Bartosz Proniewski,
Joanna Czarny,
Marta Smęda,
Barbara Sitek,
Agnieszka Zakrzewska,
Jerzy A. Zoladz,
Stefan Chłopicki
Publication year - 2018
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/mss.0000000000001589
Subject(s) - thrombogenicity , nitric oxide , thrombus , medicine , superoxide , chemistry , aerobic exercise , nitrite , cardiology , endocrinology , platelet , nitrate , biochemistry , organic chemistry , enzyme
An acute bout of strenuous exercise in humans results in transient impairment of nitric oxide (NO)-dependent function, but it remains unknown whether this phenomenon is associated with increased risk of thrombotic events after exercise. This study aimed to evaluate effects of a single bout of exhaustive running in mice on the balance of vascular NO/reactive oxygen species production, and on thrombogenicity.