Open AccessMitochondrial Dysfunction
Author(s) -
Kevin E. Conley,
Sharon A. Jubrias,
Catherine E. Amara,
David J. Marcinek
Publication year - 2007
Publication title -
exercise and sport sciences reviews
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 99
eISSN - 1538-3008
pISSN - 0091-6331
DOI - 10.1249/jes.0b013e31803e88e9
Subject(s) - in vivo , medicine , intervention (counseling) , mitochondrion , biology , physical medicine and rehabilitation , physiology , bioinformatics , neuroscience , microbiology and biotechnology , genetics , psychiatry
Innovative noninvasive methods open a new window on the cell in vivo. This window reveals that the tempo of mitochondrial dysfunction with age varies among muscles and in proportion to Type II muscle fiber content. Exercise training can reverse age-related dysfunction, thereby providing an intervention to slow the pace of aging and disability in the elderly.