Open AccessSynergy between Acute Intermittent Hypoxia and Task-Specific Training
Author(s) -
Joseph F. Welch,
Tommy W. Sutor,
Alicia Vose,
Raphael R. Perim,
Emily J. Fox,
Gordon S. Mitchell
Publication year - 2020
Publication title -
exercise and sport sciences reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 99
eISSN - 1538-3008
pISSN - 0091-6331
DOI - 10.1249/jes.0000000000000222
Subject(s) - hypoxia (environmental) , intermittent hypoxia , neuroscience , task (project management) , spinal cord injury , physical medicine and rehabilitation , medicine , spinal cord , psychology , anesthesia , chemistry , oxygen , management , organic chemistry , obstructive sleep apnea , economics
Acute intermittent hypoxia (AIH) and task-specific training (TST) synergistically improve motor function after spinal cord injury; however, mechanisms underlying this synergistic relation are unknown. We propose a hypothetical working model of neural network and cellular elements to explain AIH-TST synergy. Our goal is to forecast experiments necessary to advance our understanding and optimize the neurotherapeutic potential of AIH-TST.