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Training-Induced Neural Plasticity and Strength Are Amplified After Stroke
Author(s) -
Yipeng Sun,
E. Paul Zehr
Publication year - 2019
Publication title -
exercise and sport sciences reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 99
eISSN - 1538-3008
pISSN - 0091-6331
DOI - 10.1249/jes.0000000000000199
Subject(s) - neuroplasticity , stroke (engine) , physical medicine and rehabilitation , neuroscience , psychology , plasticity , structural plasticity , medicine , engineering , thermodynamics , mechanical engineering , physics
Following stroke, sensorimotor brain networks and descending regulation are compromised but spinal interlimb neural connections remain morphologically intact. After cross-education strength and locomotion training, amplified neural plasticity and functional responses are observed in chronic stroke compared with neurologically intact participants. We hypothesize that poststroke neuroplasticity is amplified because of the involvement of interlimb neural connections that persist from our quadrupedal ancestry.

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