Open AccessPerformance Limitations in Heart Transplant Recipients
Author(s) -
Wesley J. Tucker,
Rhys Beaudry,
T. Jake Samuel,
Michael D. Nelson,
Martin Halle,
Aaron L. Baggish,
Mark J. Haykowsky
Publication year - 2018
Publication title -
exercise and sport sciences reviews
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 99
eISSN - 1538-3008
pISSN - 0091-6331
DOI - 10.1249/jes.0000000000000149
Subject(s) - heart transplantation , medicine , intensive care medicine , heart failure , cardiology
We hypothesize that the reduced peak aerobic power (peak V˙O2) after heart transplantation is due to impaired cardiovascular and skeletal muscle function, and its improvement with short-term (≤1 yr) exercise training is primarily due to favorable skeletal muscle adaptations. Furthermore, the increased peak V˙O2 with long-term (>2 yr) training is primarily mediated by cardiac (sympathetic) reinnervation.