Open AccessCirculating microRNA as Emerging Biomarkers of Exercise
Author(s) -
Manuel FernándezSanjurjo,
David de Gonzalo-Calvo,
Benjamín FernándezGarcía,
Sergio DíezRobles,
Ángel Martínez-Canal,
Hugo Olmedillas,
Alberto Dávalos,
Eduardo IglesiasGutiérrez
Publication year - 2018
Publication title -
exercise and sport sciences reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 99
eISSN - 1538-3008
pISSN - 0091-6331
DOI - 10.1249/jes.0000000000000148
Subject(s) - microrna , biomarker , diagnostic biomarker , bioinformatics , biomarker discovery , medicine , computational biology , biology , proteomics , gene , genetics
An interest has recently emerged in the role of circulating microRNAs (c-miRNAs) as posttranscriptional regulators, intercellular communicators and, especially, as potential biomarkers of the systemic response to acute exercise and training. We propose that, with the limited, heterogeneous, and mainly descriptive information currently available, c-miRNAs do not provide a reliable biomarker of exercise in healthy or diseased individuals.