Open AccessTime and Sample Site Dependency of the Optimized CO-Rebreathing Method
Author(s) -
Christopher J. Gore,
Pitre C. Bourdon,
Sarah M. Woolford,
Laura M. Ostler,
Annette Eastwood,
G. C. Scroop
Publication year - 2006
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/01.mss.0000222848.35004.41
Subject(s) - carboxyhemoglobin , venous blood , anesthesia , capillary action , hemoglobin , medicine , bolus (digestion) , limits of agreement , chemistry , surgery , nuclear medicine , carbon monoxide , biochemistry , materials science , composite material , catalysis
A new method to estimate hemoglobin mass (Hbmass) requires capillary blood and rebreathing a carbon-monoxide (CO) bolus for 2 min. We hypothesized that incomplete circulatory mixing of CO could confound this method, so we compared capillary with venous blood to determine whether sampling site altered the percentage of carboxyhemoglobin (%HbCO) and the reliability and accuracy of the "2-min Hbmass." The conventional 20-min CO-rebreathing procedure was used as the Hbmass criterion.