Open AccessA pictographic essay on blood and tissue oxygen transport
Author(s) -
W. N. Stainsby,
Bruce D. Snyder,
H Welch
Publication year - 1988
Publication title -
medicine and science in sports and exercise
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.703
H-Index - 224
eISSN - 1530-0315
pISSN - 0195-9131
DOI - 10.1249/00005768-198806000-00001
Subject(s) - context (archaeology) , oxygen , oxygen transport , partial pressure , ischemia , venous blood , hypoxia (environmental) , chemistry , anesthesia , cardiology , medicine , biology , paleontology , organic chemistry
This review describes the transport of oxygen from ambient air to mitochondria in the cells. Using simple equations and diagrams, the presentation illustrates the variables which determine the magnitude of each of the three major steps in the partial pressure of O2 along the passage, from: (i) ambient air to alveolar gas; (ii) arterial blood to venous blood; and (iii) capillary blood to tissue. The emphasis is on steps (ii) and (iii), and how they are modified from the normoxic case by ischemia, anemia, hypoxia, and increased VO2. The basic context of step (iii) is the Krogh model. This model, despite its limitations, is proposed as conceptually useful in analyzing whole-body or tissue O2 transport.