Open AccessDifferences in Liver Parenchyma are Measurable with CT Radiomics at Initial Colon Resection in Patients that Develop Hepatic Metastases from Stage II/III Colon Cancer
Author(s) -
John M. Creasy,
Kristen Cunanan,
Jayasree Chakraborty,
John C. McAuliffe,
Joanne F. Chou,
Mithat Gönen,
Victoria S Kingham,
Martin R. Weiser,
Vinod P. Balachandran,
Jeffrey A. Drebin,
T. Peter Kingham,
William R. Jarnagin,
Michael I. D’Angelica,
K. G. Richard,
Amber L. Simpson
Publication year - 2020
Publication title -
annals of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.764
H-Index - 173
eISSN - 1534-4681
pISSN - 1068-9265
DOI - 10.1245/s10434-020-09134-w
Subject(s) - medicine , surgical oncology , liver parenchyma , colorectal cancer , radiomics , stage (stratigraphy) , hepatectomy , radiology , retrospective cohort study , parenchyma , cancer , cohort , resection , gastroenterology , surgery , pathology , biology , paleontology
Currently, there are no methods to identify patients with an increased risk of liver metastases to guide patient selection for liver-directed therapies. We tried to determine whether quantitative image features (radiomics) of the liver obtained from preoperative staging CT scans at the time of initial colon resection differ in patients that subsequently develop liver metastases, extrahepatic metastases, or demonstrate prolonged disease-free survival.