Open AccessAxillary Downstaging in Occult Primary Breast Cancer After Neoadjuvant Chemotherapy
Author(s) -
Astrid Botty van den Bruele,
Jessica A. Lavery,
George Plitas,
Melissa Pilewskie
Publication year - 2020
Publication title -
annals of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.764
H-Index - 173
eISSN - 1534-4681
pISSN - 1068-9265
DOI - 10.1245/s10434-020-08863-2
Subject(s) - medicine , breast cancer , axilla , sentinel lymph node , surgical oncology , biopsy , oncology , stage (stratigraphy) , occult , neoadjuvant therapy , chemotherapy , axillary lymph node dissection , cancer , pathology , paleontology , alternative medicine , biology
Neoadjuvant chemotherapy (NAC) is increasingly used for clinically node-positive (cN+) tumors with intact primary breast cancer (IPBC) to downstage the axilla, and those who convert to cN0 may be eligible for sentinel lymph node biopsy (SLNB). Rates of axillary downstaging in occult primary breast cancer (OPBC) are unknown.