Open AccessAssociation of RAS Mutation Location and Oncologic Outcomes After Resection of Colorectal Liver Metastases
Author(s) -
Lily V. Saadat,
Thomas Boerner,
Debra A. Goldman,
Mithat Gönen,
Timothy L. Frankel,
Efsevia Vakiani,
T. Peter Kingham,
William R. Jarnagin,
Alice C. Wei,
Kevin C. Soares,
David B. Solit,
Michael I. D’Angelica
Publication year - 2020
Publication title -
annals of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.764
H-Index - 173
eISSN - 1534-4681
pISSN - 1068-9265
DOI - 10.1245/s10434-020-08862-3
Subject(s) - kras , medicine , neuroblastoma ras viral oncogene homolog , surgical oncology , exon , colorectal cancer , gastroenterology , exact test , retrospective cohort study , oncology , confidence interval , mutation , cancer , biology , gene , genetics
RAS mutations are prognostic for patients with metastatic colorectal cancer (mCRC). We investigated clinical, pathologic, and survival differences based on RAS exon for patients with colorectal liver metastases (CRLM).