Open AccessLobular Histology Does Not Predict the Need for Axillary Dissection Among ACOSOG Z0011-Eligible Breast Cancers
Author(s) -
Anita Mamtani,
Emily C. Zabor,
Michelle Stempel,
Monica Morrow
Publication year - 2019
Publication title -
annals of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.764
H-Index - 173
eISSN - 1534-4681
pISSN - 1068-9265
DOI - 10.1245/s10434-019-07536-z
Subject(s) - medicine , axillary lymph node dissection , lymphovascular invasion , breast cancer , invasive lobular carcinoma , surgical oncology , radiology , sentinel lymph node , cancer , oncology , metastasis , invasive ductal carcinoma
The American College of Surgeons Oncology Group (ACOSOG) Z0011 trial demonstrated that axillary lymph node dissection (ALND) may be omitted for women with two or fewer positive sentinel nodes (SLNs) undergoing breast-conservation therapy (BCT). Lobular histology comprises a minority of patients, and applicability to these discohesive cancers has been questioned.