Open AccessAnalysis of Factors Associated with Outcome in Patients Undergoing Isolated Hepatic Perfusion for Unresectable Liver Metastases from Colorectal Center
Author(s) -
H. Richard Alexander,
David L. Bartlett,
Steven K. Libutti,
James F. Pingpank,
Douglas L. Fraker,
Richard E. Royal,
Seth M. Steinberg,
Cynthia Helsabeck,
Tatiana Beresneva
Publication year - 2009
Publication title -
annals of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.764
H-Index - 173
eISSN - 1534-4681
pISSN - 1068-9265
DOI - 10.1245/s10434-009-0482-9
Subject(s) - medicine , melphalan , colorectal cancer , surgical oncology , gastroenterology , chemotherapy , carcinoembryonic antigen , proportional hazards model , oxaliplatin , survival analysis , oncology , surgery , cancer
To define the indications for hyperthermic isolated hepatic perfusion (IHP) in patients with unresectable liver metastases (LM) from colorectal cancer (CRC) with particular focus on IHP's utility as a second-line option for patients whose tumors have progressed following combination systemic chemotherapy treatment.