Open AccessCollagen (I) homotrimer potentiates the osteogenesis imperfecta (oim) mutant allele and reduces survival in male mice
Author(s) -
Katie J Lee,
Lisa Rambault,
George BouGharios,
Peter Clegg,
Riaz Akhtar,
Gabriela Czanner,
R. van ’t Hof,
Elizabeth G. CantyLaird
Publication year - 2022
Publication title -
disease models and mechanisms
Language(s) - English
Resource type - Journals
eISSN - 1754-8411
pISSN - 1754-8403
DOI - 10.1242/dmm.049428
Subject(s) - osteogenesis imperfecta , heterozygote advantage , compound heterozygosity , allele , mutant , wild type , haploinsufficiency , type i collagen , phenotype , chemistry , endocrinology , genetic model , medicine , genetics , microbiology and biotechnology , biology , gene , anatomy