Open AccessStimulating the sir2–spargel axis rescues exercise capacity and mitochondrial respiration in a Drosophila model of Barth syndrome
Author(s) -
Deena Damschroder,
Rubén Zapata-Pérez,
Kristin Richardson,
Frédéric M. Vaz,
Riekelt H. Houtkooper,
Robert Wessells
Publication year - 2022
Publication title -
disease models and mechanisms
Language(s) - English
Resource type - Journals
eISSN - 1754-8411
pISSN - 1754-8403
DOI - 10.1242/dmm.049279
Subject(s) - cardiolipin , mitochondrion , biology , mutant , drosophila melanogaster , context (archaeology) , nad+ kinase , microbiology and biotechnology , biochemistry , phospholipid , gene , enzyme , paleontology , membrane