Membrane trafficking in health and disease | Zendy

Rebecca Yarwood | Zendy; John Hellicar | Zendy; Philip Woodman | Zendy; Martin Lowe | Zendy

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Membrane trafficking in health and disease

Author(s) -

Rebecca Yarwood,

John Hellicar,

Philip Woodman,

Martin Lowe

Publication year - 2020

Publication title -

disease models and mechanisms

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.327

H-Index - 83

eISSN - 1754-8411

pISSN - 1754-8403

DOI - 10.1242/dmm.043448

Subject(s) - function (biology) , disease , biology , microbiology and biotechnology , computational biology , medicine , pathology

Membrane trafficking pathways are essential for the viability and growth of cells, and play a major role in the interaction of cells with their environment. In this At a Glance article and accompanying poster, we outline the major cellular trafficking pathways and discuss how defects in the function of the molecular machinery that mediates this transport lead to various diseases in humans. We also briefly discuss possible therapeutic approaches that may be used in the future treatment of trafficking-based disorders.

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