Open AccessReturn of Gonadal Function with Resection of Nonfunctioning Pituitary Adenoma
Author(s) -
K. Patrick Ober,
David L. Kelly
Publication year - 1988
Publication title -
neurosurgery/neurosurgery online
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.485
H-Index - 34
eISSN - 1081-1281
pISSN - 0148-396X
DOI - 10.1227/00006123-198802000-00019
Subject(s) - medicine , chromophobe cell , pituitary adenoma , endocrine system , testosterone (patch) , adenoma , endocrinology , pituitary gland , resection , pituitary tumors , pituitary neoplasm , neurosurgery , hormone , surgery , carcinoma , clear cell
A 42-year-old man with severe testicular failure (testosterone 24 ng/dl, normal 300-1100) was found to have a nonfunctioning chromophobe pituitary adenoma. Resection of the pituitary tumor resulted in recovery of gonadal function (testosterone 359 ng/dl). Hypogonadism caused by pituitary adenomas is usually attributed to either hyperprolactinemia or irreversible destruction of normal pituitary tissue, neither of which is applicable to this patient. The recovery of our patient's gonadal function after operation suggests that a reversible compression of viable tissue or impairment of hypothalamic-pituitary communications was responsible for his endocrine deficiency. (Neurosurgery 22:386-387, 1988)