Open AccessPathophysiology of Cerebrospinal Fluid in Head Injury: Part 2 Biochemical Markers for Central Nervous System Trauma
Author(s) -
Roy A.E. Bakay,
Kevin Sweeney,
James H. Wood
Publication year - 1986
Publication title -
neurosurgery/neurosurgery online
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.485
H-Index - 34
eISSN - 1081-1281
pISSN - 0148-396X
DOI - 10.1227/00006123-198603000-00026
Subject(s) - medicine , cerebrospinal fluid , head trauma , central nervous system , head injury , pathophysiology , pathology , lesion , traumatic brain injury , brain trauma , nervous system , surgery , psychiatry
Many substances are released into the cerebrospinal fluid after head injury. The study of these substances and their relationship to the severity and outcome of head trauma has lead to the search for biochemical markers to aid in the quantification of the severity of the lesion and serve as a prognostic guide. The authors review the potential usefulness of biochemical markers, qualities of an ideal marker, and several potential enzymes that may be utilized as markers in central nervous system trauma.