Open AccessServo-controlled Lumbar Infusions
Author(s) -
Frederick H. Sklar,
C. W. Beyer,
Murugappan Ramanathan,
I. Elashvili,
Paul R. Cooper,
W. K. Clark
Publication year - 1978
Publication title -
neurosurgery/neurosurgery online
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.485
H-Index - 34
eISSN - 1081-1281
pISSN - 0148-396X
DOI - 10.1227/00006123-197809000-00007
Subject(s) - medicine , cerebrospinal fluid , lumbar , lumbar puncture , servo , absorption rate , anesthesia , statistical significance , compartment (ship) , surgery , chromatography , mechanical engineering , chemistry , engineering , oceanography , geology
The variable rate lumbar subarachnoid infusion technique allows rapid quantitative study of the cerebrospinal fluid (CSF) compartment. Numerous pressure plateaus are studied in a brief time period with a servo-controlled system. The test determines the difference between rates of CSF absorption and formation as a function of pressure. On-line computer data analysis increases experimental efficiency to guarantee statistical significance. Animal and patient data are presented in the report.