Inhibition by Local Bupivacaine-Releasing Microspheres of Acute Postoperative Pain from Hairy Skin Incision | Zendy

Rachit Ohri | Zendy; Jeffrey Chi-Fei Wang | Zendy; Phillip D. Blaskovich | Zendy; Lan Pham | Zendy; Daniel Costa | Zendy; Gary A. Nichols | Zendy; William Hildebrand | Zendy; Nelson Scarborough | Zendy; Clifford Herman | Zendy; Gary R. Strichartz | Zendy

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Inhibition by Local Bupivacaine-Releasing Microspheres of Acute Postoperative Pain from Hairy Skin Incision

Author(s) -

Rachit Ohri,

Jeffrey Chi-Fei Wang,

Phillip D. Blaskovich,

Lan Pham,

Daniel Costa,

Gary A. Nichols,

William Hildebrand,

Nelson Scarborough,

Clifford Herman,

Gary R. Strichartz

Publication year - 2013

Publication title -

anesthesia and analgesia

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.404

H-Index - 201

eISSN - 1526-7598

pISSN - 0003-2999

DOI - 10.1213/ane.0b013e3182a00851

Subject(s) - bupivacaine , medicine , anesthesia , hyperalgesia , allodynia , microsphere , surgery , nociception , receptor , chemical engineering , engineering

Acute postoperative pain causes physiological deficits and slows recovery. Reduction of such pain by local anesthetics that are delivered for several days postoperatively is a desirable clinical objective, which is approached by a new formulation and applied in animal studies reported here.

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