Open AccessA Comparison Between Dexamethasone and Methylprednisolone for Vomiting Prophylaxis After Tonsillectomy in Inpatient Children
Author(s) -
Marie T. Aouad,
Viviane G. Nasr,
Vanda G. YazbeckKaram,
Mohammad A. Bitar,
Micheline Bou Khalil,
Ornella Beyrouthy,
Diala Harfouche,
Norma Terrin,
Sahar M. Siddik-Sayyid
Publication year - 2012
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0b013e3182652a6a
Subject(s) - medicine , vomiting , methylprednisolone , tonsillectomy , dexamethasone , anesthesia , antiemetic , incidence (geometry) , surgery , corticosteroid , physics , optics
The frequent incidence of postoperative vomiting in children undergoing tonsillectomy, in addition to the occurrence of severe pain, may delay postoperative oral intake and lead to increased risk of dehydration. Thus, prophylactic therapy is indicated in this high-risk group. Glucocorticoids, such as dexamethasone and methylprednisolone, have anti-inflammatory and antiemetic properties with dexamethasone being frequently used. We hypothesized that methylprednisolone should be noninferior to dexamethasone for the prevention of vomiting in children after tonsillectomy.