Open AccessEffects of Intrathecal Morphine on Transcranial Electric Motor-Evoked Potentials in Adolescents Undergoing Posterior Spinal Fusion
Author(s) -
Paul A. Stricker,
Anthony K. Sestokas,
Daniel M. Schwartz,
Vidya M. Bhalodia,
Ankit Pahwa,
John P. Dormans,
Lia L. LaBrant,
Beverly J. Burgess,
F. Wickham Kraemer,
Arjunan Ganesh
Publication year - 2012
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0b013e31824e5d86
Subject(s) - medicine , anesthesia , morphine , evoked potential , audiology
Intrathecal morphine (ITM) provides effective analgesia after posterior spinal fusion (PSF). Although most anesthetic drugs have well-characterized effects on evoked potentials, there is little data on the effects of ITM on transcranial electric motor-evoked potentials (tceMEPs). We performed this study to assess the effects of ITM on tceMEPs in the first 30 minutes after administration. We hypothesized that administration of ITM in doses currently used at our institution would not significantly affect mean tceMEP amplitudes and latencies of an ITM study group relative to control patients who did not receive the drug.