Open AccessED50 and Recovery Times After Propofol in Rats with Graded Cirrhosis
Author(s) -
Zhenzhou Li,
Xue-Xin Chen,
Meng Ji,
Liqin Deng,
Haijun Ma,
Marie Csete,
Lize Xiong
Publication year - 2012
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0b013e3182367a24
Subject(s) - medicine , anesthesiology , intensive care medicine , closed loop , setpoint , propofol , anesthesia , computer science , control engineering , artificial intelligence , engineering
Patients with end-stage liver disease have increased sensitivity to general anesthetics. In this study, we sought to quantify sensitivity to propofol as a function of the degree of liver disease, in a rat model of cirrhosis.