Open AccessImplications of Anesthesia in Children with Long QT Syndrome
Author(s) -
Aruna T. Nathan,
Darryl H. Berkowitz,
Lisa M. Montenegro,
Susan C. Nicolson,
Victoria L. Vetter,
David R. Jobes
Publication year - 2011
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0b013e3182121d57
Subject(s) - medicine , long qt syndrome , anesthesia , perioperative , ondansetron , retrospective cohort study , antiemetic , adverse effect , bradycardia , qt interval , nausea , heart rate , blood pressure
Patients with congenital long QT syndrome (LQTS) are susceptible to an episodic malignant ventricular tachyarrhythmia known as torsade de pointes, which can result in a cardiac arrest and death. Patients can suffer severe cardiac events resulting in syncope, seizures, and sudden cardiac death during times of physical and emotional stress and when exposed to certain drugs including anesthetics. We describe the occurrence of perioperative adverse events (AEs) related to arrhythmias in children with congenital LQTS exposed to volatile general anesthesia and describe associated risk factors.