Inhaled Carbon Monoxide Prevents Acute Kidney Injury in Pigs After Cardiopulmonary Bypass by Inducing a Heat Shock Response | Zendy

Ulrich Goebel | Zendy; Matthias Siepe | Zendy; Christian I. Schwer | Zendy; David Schibilsky | Zendy; Katharina Foerster | Zendy; Jens Neumann | Zendy; Thorsten Wiech | Zendy; HansJoachim Priebe | Zendy; Christian Schlensak | Zendy; Torsten Loop | Zendy

Open Access

Inhaled Carbon Monoxide Prevents Acute Kidney Injury in Pigs After Cardiopulmonary Bypass by Inducing a Heat Shock Response

Author(s) -

Ulrich Goebel,

Matthias Siepe,

Christian I. Schwer,

David Schibilsky,

Katharina Foerster,

Jens Neumann,

Thorsten Wiech,

HansJoachim Priebe,

Christian Schlensak,

Torsten Loop

Publication year - 2010

Publication title -

anesthesia and analgesia

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.404

H-Index - 201

eISSN - 1526-7598

pISSN - 0003-2999

DOI - 10.1213/ane.0b013e3181e0cca4

Subject(s) - medicine , acute kidney injury , cardiopulmonary bypass , cystatin c , shock (circulatory) , creatinine , heat shock protein , renal function , pharmacology , anesthesia , biochemistry , chemistry , gene

Cardiopulmonary bypass (CPB) may be associated with acute kidney injury (AKI). Inhaled carbon monoxide (CO) is cyto- and organ-protective. We hypothesized that pretreatment with inhaled CO prevents CPB-associated AKI.

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