Open AccessHelium Breathing Provides Modest Antiinflammatory, but No Endothelial Protection Against Ischemia-Reperfusion Injury in Humans In Vivo
Author(s) -
Eliana Lucchinetti,
Jürgen Wacker,
Christian Maurer,
Marius Keel,
Luc Härter,
Kathrin Zaugg,
Michael Zaugg
Publication year - 2009
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0b013e3181a27e4b
Subject(s) - medicine , reperfusion injury , ischemia , anesthesia , proinflammatory cytokine , inhalation , pharmacology , endothelium , endothelial dysfunction , inflammation
The noble gas helium is devoid of anesthetic effects, and it elicits cardiac preconditioning. We hypothesized that inhalation of helium provides protection against postocclusive endothelial dysfunction after ischemia-reperfusion of the forearm in humans.