Open AccessThe Influence of Aprotinin and Tranexamic Acid on Platelet Function and Postoperative Blood Loss in Cardiac Surgery: Retracted
Author(s) -
Andinet Mengistu,
Kerstin D. Röhm,
Joachim Boldt,
Jochen Mayer,
Stefan Suttner,
Swen N. Piper
Publication year - 2008
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0b013e31817b7732
Subject(s) - aprotinin , medicine , tranexamic acid , thrombelastography , cardiopulmonary bypass , anesthesia , blood loss , platelet , cardiac surgery , antifibrinolytic , surgery
Antifibrinolytic drugs including aprotinin and tranexamic acid are currently used in cardiac surgery to reduce postoperative bleeding and transfusion requirements, and may have different effects on platelets. We therefore evaluated platelet function after cardiopulmonary bypass (CPB) and cardiac surgery to determine the effect of either aprotinin or tranexamic acid.