Open AccessSugammadex Versus Neostigmine for Recovery of Respiratory Muscle Strength Measured by Ultrasonography in the Postextubation Period: A Randomized Controlled Trial
Author(s) -
Chanyan Huang,
Xuan Wang,
Gao S,
Wenyi Luo,
Xu Zhao,
Qian Zhou,
Wenqi Huang,
Ying Xiao
Publication year - 2022
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000006219
Subject(s) - sugammadex , medicine , neostigmine , anesthesia , rocuronium , pacu , confidence interval , diaphragm (acoustics) , isometric exercise , neuromuscular blockade , surgery , intubation , physics , acoustics , loudspeaker
Although sugammadex is well known for its use in reducing the incidence of residual neuromuscular blockade, this has not always been translated to improved clinical measures of postoperative respiratory muscle strength. Expiratory muscles play an important role in airway clearance and inspiratory muscle capacity augmentation, yet they have not been well studied. Therefore, we tested the hypothesis on whether sugammadex could enhance expiratory muscle strength recovery more completely than neostigmine in the immediate postextubation period.