Open AccessAssociation Between Antifibrinolytic Therapy and Perioperative Outcomes in Patients With Coronary Artery Stents Undergoing Noncardiac Surgery
Author(s) -
Michael R. Boswell,
Mark M. Smith,
Ryan D. Frank,
Michael J. Brown,
Arnoley S. Abcejo,
Todd M. Kor,
Rajiv Gulati,
Bruce P. Smith
Publication year - 2021
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.404
H-Index - 201
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000005522
Subject(s) - medicine , perioperative , intensive care unit , cardiology , stent , confounding , cardiac surgery , retrospective cohort study , coronary artery bypass surgery , percutaneous coronary intervention , propensity score matching , surgery , artery , myocardial infarction
Patients with existing coronary artery stents are at an increased risk for major adverse cardiac events (MACEs) when undergoing noncardiac surgery (NCS). Although the use of antifibrinolytic (AF) therapy in NCS has significantly increased in the past decade, the relationship between perioperative AF use and its association with MACEs among patients with existing coronary artery stents has yet to be assessed. In this study, we aim to evaluate the association of MACEs in patients with existing coronary artery stents who receive perioperative AF therapy during orthopedic surgery.