Open AccessComparative Efficacy of 6 Topical Pharmacological Agents for Preventive Interventions of Postoperative Sore Throat After Tracheal Intubation: A Systematic Review and Network Meta-analysis
Author(s) -
Ge Wang,
Qi Yang,
Linquan Wu,
Guichun Jiang
Publication year - 2021
Publication title -
anesthesia and analgesia/anesthesia and analgesia
Language(s) - English
Resource type - Journals
eISSN - 1526-7598
pISSN - 0003-2999
DOI - 10.1213/ane.0000000000005521
Subject(s) - medicine , lidocaine , placebo , anesthesia , sore throat , randomized controlled trial , relative risk , number needed to treat , meta analysis , cochrane library , odds ratio , acute pharyngitis , analgesic , confidence interval , surgery , pharyngitis , alternative medicine , pathology
Topical pharmacological agents typically used to treat postoperative sore throat (POST) after tracheal intubation include nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, lidocaine, Glycyrrhiza (licorice), and N-methyl-d-aspartate (NMDA) receptor antagonists (including ketamine and magnesium). However, the optimal prophylactic drug remains elusive.